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Flow Measurement Technologies: What Bioengineers Should Know

By John Haberstock03 Mar 2020

Transonic pioneered 2 foundational flow measurement technologies. The first was transit time ultrasound flow measurement, created for biomedical use by founder Cor Drost. The technology uses non-invasive ultrasound and measures the actual amount of blood flowing through the vessel, duct or flexible plastic tube directly with high accuracy, without manipulating the conduit in a way that would alter the flow that is being measured.

You can use transit time ultrasound technology to make measurements in in-vitro Screen Shot 2020-02-10 at 2.26.26 PMbench-top models and in-vivo animal models.

Dr. Nikolai Krivitski expanded Transonic’s technological scope when he developed ultrasound dilution technology. Dr. Krivitski, who was well-versed in classic dilution technology, had an “aha!” insight that existing transit-time ultrasound technology could be married to classic indicator dilution technology to create “ultrasound dilution technology” with enhanced measurement capabilities.

Then Dr. Krivitski had another “aha!” insight: Transonic’s transit-time ultrasound technology hardware could measure desired parameters during hemodialysis that could help save the lives of end-stage-renal-disease patients undergoing hemodialysis.

What can Transit-Time Ultrasound Technology and Ultrasound Dilution Technology Measure?

Transit time ultrasound measures:

  • Liquid flow through a vessel/tube
  • Ultrafiltration rate
  • Liquid properties
  • Zero-flow & low-flow resolution
  • Total liquid volume
  • Bubble detection

Ultrasound dilution technology measures:

  • Vascular access flow/patency
  • Recirculation
  • Cardiac output
  • Central blood volume
  • Filter volume and clotting

Learn more about additional Transonic measurement technologies, the transit-time flow measurement theory of operation, the five advantages to transit-time flow measurement technology and much more in this guide